AutoGen
Microsoft's open source framework for building multi-agent AI apps
27 tools in our directory are marked as best for Python developers, from 11 sections: AI Agents & Assistants (8), Frameworks (4), Dev Utilities (3), Testing & QA (3) and 7 more sections.

Microsoft's open source framework for building multi-agent AI apps

Open source community and framework for multi-agent systems

Measures which Python code runs during your tests

High-level Python framework for building database-driven web apps

Open source Python library for building data loading pipelines

Framework for programming LLM pipelines with typed signatures

Python framework for building APIs with type hints and automatic docs

Python framework for building MCP servers and clients

Lightweight Python WSGI framework for web apps and APIs

Open source database layer on Postgres with a typed schema

Property-based testing library for Python that finds edge cases

Library for getting structured, validated data from LLM output


Low-level framework for stateful, long-running agents as graphs

Open source reactive Python notebook stored as plain Python files

Static site generator for project docs written in Markdown

Lightweight Python SDK for agents, handoffs and guardrails


Type-safe Python agent framework with many model providers

Official package index for finding and installing Python packages


Official reference, tutorial and guides for the Python language


Builds documentation sites from reStructuredText or Markdown files

Python SQL toolkit and ORM with full SQL power and flexibility

Fast Python package and project manager written in Rust

Open source Django CMS for flexible, editor-friendly sites
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